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All formats used HCT116 colon cancer cells grown for 4 days and treated with compounds for 48 hours before assay

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Reactive astrocytes are a subtype of astrocyte that become activated in response to diseased states of the brain, and can occupy one of two cell states, one being neurotoxic and the other being neuroprotective (Liddelow et al., 2017)

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E End-of-Use (Withdrawal): Problems arising when stopping or tapering the drug