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NHS treatment guidance describes a loading course followed by maintenance injections every two to three months for many people, while a diet-related deficiency may need less

Future trials should ideally close the gaps in evidence for the pharmacological and non-pharmacological treatment of these, still underestimated, disturbances in the specific setting of PD

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The diabetes drug metformin and all the proton pump inhibitors (PPIs) such as omeprazole ( Prilosec ), esomeprazole ( Nexium ), lansoprazole ( Prevacid ) and pantoprazole ( Protonix ) can interfere with vitamin B12 absorption