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Nguyen NT, Umbaugh DS, Smith S, et al

Toxicology, 9: 47-57

DM, if left untreated or treated poorly, causes not only well-known complications such as coronary heart disease, stroke, peripheral neuropathy, diabetic ulcers, diabetic kidney disease, and retinopathy but also emerging complications that have been reported, such as cancer, infection, liver disease, affective disorder, and functional disability, as well as cognitive disability that leads to high morbidity and mortality [93,94,95]

In this section twelve mice were divided into four groups (0d, 1d, 3d and 7d) with 3 mice in each group