3-methylindole glutathione Detection of Reactive Metabolites Using Isotope-Labeled Trapping and Simultaneous Neutral Loss and Precursor Ion Scanning with Ultra-High-Pressure Liquid Chromatography Triple Quadruple Mass Spectrometry Skatole-d8 (3 Proposed scheme for DCE metabolism.

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However, it seems that eukaryotic proteasomes fail to cleave and eliminate pathogenic protein species with repeats greater than 25Q residues

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The expression profile of growth factors involved in OPC recruitment (PDGFRa, FGF2) and in OPC differentiation (IGF1, TGF1) following demyelination is altered in old mice, in which the upregulation of these factors is both weaker and delayed (Hinks and Franklin, 2000)