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The mechanism appears to involve changes in how skin bacteria produce porphyrins, compounds that can promote inflammation within hair follicles

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Rouette A, Trofimov A, Haberl D, Boucher G, Lavalle VP, DAngelo G, et al

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Using SynGO 35 to screen the DEPs in Akap11 -cKO mouse and AKAP11 -KO iNeuron, we found an enrichment in both pre- and postsynaptic compartments, sharing multiple sub-synaptic terms, including regulation of synapse assembly, SV exocytosis and endocytosis, postsynaptic membrane neurotransmitter receptor levels, and chemical synaptic transmission (Supplementary Fig