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Certain chemicals, like hydroquinone, might be dangerous if misused or used over a lengthy period

33 PFIC3 can present with pruritus, although it is often less severe than PFIC2

Large amounts are unsafe and should be avoided

Declaration of Generative AI and AI-assisted technologies in the writing process The authors confirm that there was no use of Artificial Intelligence (AI)-Assisted Technology for assisting in the writing or editing of the manuscript and no images were manipulated using AI

To partially address only the issue of recessiveness, we used our maps to score diploid genotypes of patients with homocystinuria (Fig