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doi: 10.1194/jlr.R046599

Accumulation of free radicals and increased pro-inflammatory cytokines such as IL-1 and IL-6, combined with decreased expression of anti-inflammatory cytokines such as IL-10 and IL-4, contribute to the maintenance of the senescent inflammatory state (Ye and Johnson, 2001

When your blood carries less oxygen than it should, often because of low iron, vitamin B12, or folate, your muscles fatigue and ache more easily with normal use, including the muscles of your jaw

However, orthopaedic-specific clinical evidence supporting improved healing or postoperative recovery is lacking

The beneficial therapeutic effects of UA in acute and chronic forms of mouse experimental allergic encephalomyelitis (EAE) have also been shown [156]