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Eventually the muscle heals, but some of the muscle fibers inside the piriformis muscle are replaced by scar tissue

5B) was most likely due to its flux into NADP(H) production, where NADPH is required by xenobiotic detoxification enzymes for the metabolism of Dox

ABC, ATP-Binding Cassette

However, the clinical success of these combination therapies is highly contingent upon a deeper understanding of the TME and the underlying mechanisms of resistance, which can vary considerably across different cancer types