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suis infected animals receiving the Gln-supplemented diet, only an upregulation of IL-1 was noted, whereas mRNA expression levels of other cytokines dropped back to the levels of uninfected control animals

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Am J Nephrol 46:7381

However, more recent phase III findings indicated that iclepertin did not achieve significant improvements in cognitive or functional outcomes compared with placebo after six months of treatment

A total of 36 animals were used, distributed in three experimental groups with 12 rats each: (I)A group of healthy not treated, sentinel animals was used to obtain echocardiographic and biochemical reference values at the end of the intoxication period