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The result is an abnormally wired brain

Although many studies have investigated various oral supplements and medications, such as vitamin E, Potaba (potassium amino-benzoate), tamoxifen, colchicine, and carnitine, none have demonstrated significant benefits in randomized controlled trials, and scientific data do not support the use of these agents

Arch Gen Psychiatry 2011

Just briefly, 'cause it's relevant to the conversation that we've been having, you might want to be wary of any experience, any experience, no matter how it arrives, chemical, physical, emotional, or some combination, you might want to be wary of letting your dopamine go too high, and certainly you want to be wary of it going too low, because of the way that these circuits adjust

5.Gerstner T, Buesing D, Longin E, et al