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This allosteric targeting approach can effectively avoid pseudotargeting or loss of target, and the plug-and-play targeting moieties effectively improved the biocompatibility and stability of the formulation and showed good universality for various lipid-based carriers and membrane receptors

found that targeting cGAS and inhibiting lactylation modifications can promote the transition of microglia from the M1 phenotype to a repair phenotype [110], the addition of lactate has no effect on the expression of A2 astrocytes and only weakens M1 polarization process [57]

The HPV vaccine currently used in the United States, Gardasil 9, can protect against nine of the cancer-causing HPV strains

10.1123/ijspp.2019-0149 38

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