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Despite growing interest, it is not approved by regulatory agencies such as the FDA for human therapeutic use and remains strictly for laboratory research

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Given as a single agent, it promotes modest increases in survival, and these effects are enhanced when combined with oxaliplatin and/or irinotecan (FOLFOX, FOLFIRI) 2,3

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Complement activation plays a central role in the pathogenesis of AChR-positive MG, driving immune-mediated damage through MAC formation [57]