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Vitamin B12 is critical for the formation of healthy red blood cells and the maintenance of nerve cells, preventing conditions like anemia and nerve damage

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In particular, the shortage of chronic toxicological data on NPs is one of the big gaps to be closed

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Ragon BK, Daver N, Garcia-Manero G, Ravandi F, Cortes J, Kadia T, Oran B, Ohanian M, Ferrajoli A, Pemmaraju N, Kantarjian HM, Borthakur G

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Patients with DKD also exhibit increased mitochondrial division, resulting in mitochondrial fragmentation, uneven mtDNA distribution, reduced expression of enzyme complexes in the ETC, decreased OXPHOS activity, and enhanced glycolysis as a compensatory mechanism [35, 36]

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