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Although yohimbine is often found in weight loss and muscle building herbal combinations, it has not been associated with cases of clinically apparent acute liver injury

For example, a ferroptosis-prone chondrocyte cluster with high expression of ACSL4 and Tf, but low expression of FTH1 and TRPV1, has been identified in severely degenerated cartilage regions (42)

DC ferroptosis As the primary antigen-presenting cells for T cells, DCs play a crucial role in not only presenting antigen peptides and MHC class I molecules to CD8 + T cells, but also providing essential costimulatory signals for the activation of CD8 + T cells, which is vital in initiating and regulating adaptive immune responses [110]

The final concentrations of GSH for ZJ1234 and ZJ12345 reached 17.74 mM (5.45 g/L) and 19.10 mM (5.87 g/L), respectively, compared with 14.32 mM (4.40 g/L) for ZJ000 (Fig