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Moharrami Kasmaie et al., 2019

Hoffbrand AV, Moss PAH, Pettit IE

Bone density is important to maintain, because lower bone density is associated with increased risk of osteoporosis and bone fractures

In PD, there is evidence of dysregulated JAK2/STAT3 signaling

Not only inactivation of C3b in the fluid phase by Chi-bound plasmin would reduce the formation of C5 convertases but also decreases covalently bound C3b molecules at the borrelial surface