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While data for the relevant route(s) of exposure are being generated, we can use risk values set for ingestion presented in this paper along with other available information like 0.5-15 g/kg for aflatoxins in nuts, grains, dried figs, and milk and 50 g/kg for patulin in apple juice [23] after incorporating differences in ADME between oral and inhalation routes of exposure

[12] Lastly, ALA may have mild anticoagulant effects (by enhancing blood flow and endothelial function), so combining it with anticoagulant or antiplatelet drugs could very slightly increase bleeding tendency

Side effects are mild and may include temporary discomfort at the injection site, which resolves quickly

91 In UC patients, endoplasmic reticulum function may be impaired, leading to abnormal accumulation of intracellular proteins and exacerbation of the cellular inflammatory response

The maximum tolerated dose (MTD) was 30 mg/m 2 /day and the most common adverse events were thrombocytopenia and anemia