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Animal-to-human amount translation is not straightforward and requires allometric scaling, and human pharmacokinetics, safety, and efficacy remain uncharacterized in published literature

Neomycin, colchicine, para-aminosalicylic acid, or excessive alcohol intake longer than two weeks may cause malabsorption of vitamin B12. Chloramphenicol and other drugs having bone marrow suppressant properties may cause a lack of therapeutic response to vitamin B12

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