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Disclosures: Liting Chen: Nothing to Disclose, Marina Kaypaghian: Nothing to Disclose, Cheng Ji: Nothing to Disclose 1253 THE PIVOTAL ROLE OF ABCB11 ON GENETIC SUSCEPTIBILITY TO DRUG-INDUCED LIVER INJURY FROM ANABOLIC STEROIDS Paola Nicoletti 1 Samreen Zafer 1 Yi-Ju Li 2 Andrew Dellinger 3 Huiman Barnhart 2 , 1 Department of Genetics and Genomic Science, Icahn School of Medicine at Mount Sinai, New York, New Y, 2 Department of Biostatistics and Bioinformatics, Duke University, Durham, North Carolina, 3 Duke Molecular Physiology Institute, Duke University, Durham, North Carolina Background: Anabolic steroids (AS) are commonly used by bodybuilders to enhance performance and muscle mass