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The experiments employed RAMP1 knockout (KO), RAMP3 KO, and RAMP1/3 double KO mice on a 129S2/SvEv genetic background

Validation: The redesigned sensors were validated by: Comparing fluorescence intensity with the original sensor

On the extremities, the chances of complete repigmentation are low Treatments require absolute consistency : skipping phototherapy sessions or supplement doses drastically reduces effectiveness The progression can alternate phases of repigmentation and new patches Stopping treatment can lead to depigmentation of repigmented areas in certain forms The right mindset Rather than aiming for a "cure", the realistic approach consists of: Stabilizing the disease (stopping its progression) Repigmenting as much as possible the responsive areas Adapting to what cannot be repigmented (makeup, acceptance) Maintaining the gains over time Preserving overall quality of life (psychological, social) The right words: vitiligo is not a disease you "defeat" as if winning a battle

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