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the cytotoxic agent is selected from the group consisting of a vinca alkaloid, a podophyllotoxin, a taxane, a baccatin derivative, a cryptophysin, a maytansinoid, a combretastatin, and a dolastatin

Maladie de Leber : cette neuropathie optique hrditaire impose d'viter la cyanocobalamine, car elle peut acclrer l'atrophie du nerf optique et aggraver la perte de vision

By including a specific protease cleavage site between the GST tag and the recombinant protein, the tag can be cleaved off post-purification

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They can be prescribed by physicians for approved indications and sometimes for off-label use (when the physician determines its medically appropriate)