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For instance, eryptosis is suggested as an early biomarker of potentially upcoming acute complications in sickle cell disease [233]

Proteolytic enzymes like pepsin, trypsin, and chymotrypsin break the amino acid chains into fragments

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H 2 O 2 , as a relatively stable ROS, can diffuse across cell membranes and cellular compartments, acting as an important second messenger molecule involved in regulating various physiological processes such as cell proliferation, differentiation, energy metabolism, and immune responses

2-Cyano-3,12-dioxooleana-1,9-dien-28-imidazolide (CDDO-Im) directly targets mitochondrial glutathione to induce apoptosis in pancreatic cancer