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In vivo genetic ablation by Cre-mediated expression of diphtheria toxin fragment A

In in vitro studies, exposing mature human adipocytes to Cd concentrations led to the altered expression of genes involved in trace element homeostasis and heavy metal detoxification

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Further, we discuss cellular and molecular metabolic processes that may serve as key pathways in the development of MCD in utero and that may ultimately produce common mTORopathy phenotypes and sustain abnormal brain activity post-development

Their work also pointed to a shift in the redox balance in cancer cells toward a prooxidant state