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According to vegan dietitian Jack Norris, you may want to chew vitamin B12 supplement rather than swallowing it whole, and try to avoid cooking all of your B12-rich foods

doi: 10.1371/journal.pone.0189117 123 TownsendJ.BrazC

Here are some pointers to keep in mind when designing a 5-amino-1MQ dosing protocol

Intranasal delivery bypasses this and provides partial direct nose-to-brain transport through olfactory and trigeminal pathways, in addition to systemic absorption across the nasal mucosa