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& Luo, J

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In MR, genetic variants are applied as instrumental variables (IVs) to access the potential causal relationship between exposure and outcome due to the random distribution of these variants during meiosis ( Materials and methods Study design An overview of the bidirectional and unidirectional two-sample MR designs is presented in Figure 2

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[DOI] [PMC free article] [PubMed] [Google Scholar] Siedlinski M, Postma DS, van Diemen CC, Blokstra A, Smit HA, Boezen HM