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Maximum recommended doses: - In children weighing less than 40 kg, the total dose of paracetamol should not exceed 80 mg/kg/d (see Overdosage section) For information, - in children between 41 kg and 50 kg, the total dose of paracetamol should not exceed 3 g/day (see Overdosage section), - in adults and children weighing over 50 kg, THE TOTAL DOSE OF PARACETAMOL SHOULD NOT EXCEED 4 GRAMS PER DAY (see Overdose section)

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However, an important safety concern for the development of a SARS-CoV-2 vaccine or of antibody-based therapies is the potential risk of vaccine enhancement of the disease, also known as antibody-dependent enhancement (ADE) and enhanced respiratory disease (ERD) 23

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Nevertheless, further validation in larger clinical cohorts is required before such an approach can be broadly implemented