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Pharmacokinetic characterization in rats found a terminal half-life of approximately 12.7 days after intravenous administration and 8.8 days after intraperitoneal administration, with a considerably shorter half-life (approximately 335 minutes) measured in isolated rat serum

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5G) and found that anti-RGMa antibody treatment significantly improved the reduction in number and morphogenesis of DCX-positive immature neurons within the GCL (Fig

However, their pEC 50 values (pEC 50 1.011.40 g/ml) were not significantly altered at different treatment doses (120 g/ml) similar to what observed in the treatment with haloperidol (1.612.8 g/ml) (pEC50 1.311.53 g/ml)