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The dosing regimen varies depending on whether neurological symptoms are present: With neurological involvement: 1 mg intramuscularly on alternate days until no further improvement, then 1 mg every 2 months [3] [4] Without neurological involvement: 1 mg intramuscularly three times a week for 2 weeks, then 1 mg every 2-3 months for maintenance [3] [4] There is some evidence that high-dose oral B12 (1000-2000 micrograms daily) may be effective even in some malabsorption conditions, though UK practice still generally favours intramuscular treatment in these cases

B12 injections provide reliable nutrient absorption, particularly for those who: Struggle with digestive issues affecting nutrient absorption

Cost-Effectiveness: Larger vial sizes (like 15mg) offer a lower cost-per-milligram, making extended preclinical studies financially viable

I had invested my time everything into this procedure to ensure that it was going to work for me

Retrospective data collection of psoriasis treatment with fumaric acid esters in children and adolescents in Germany (KIDS FUTURE study)