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The hFcRn mouse- and scaled human parameters are summarized in Table 2

120 In myeloid cell-specific SIRT1 knockout mice, lipid toxicity or LPS stimulation induced more severe hepatic inflammation, elevated pro-inflammatory cytokine levels, and enhanced M1 macrophage polarization, highlighting the critical role of SIRT1 in preserving immune balance

Cell 148(12):213227

Tuning the elasticity of polymersomes for brain tumor targeting

Hydroxylation of naringenin by flavanone 3-hydroxylase (F3H) and flavonoid 3-hydroxylase (F3H) produces dihydroflavonols, from which dihydroflavonol reductase (DFR) produces leucoanthocyanidins (Figure 4)