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Int J Mol Med 49(5):111 Wu YJ, Muldoon LL, Neuwelt EA (2005) The chemoprotective agent N-acetylcysteine blocks cisplatin-induced apoptosis through caspase signaling pathway

535,536 Proprotein convertase subtilisin/kexin type 9 (PCSK9) is an essential regulator of LDL-C metabolism

Nat Rev Rheumatol (2016) 12:16982

(New York, New York, NY: Springer), 493510

In our study, we systematically analyzed SARS-CoV-2 protein effects on autophagy and demonstrated a mechanism by which viral ORF3a inhibits autophagosomelysosome fusion: ORF3a disrupts the assembly of the RAB7HOPS fusion machinery (Fig