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Ferroptosis, an iron-dependent form of RCD driven by GSH depletion and GPX4 inactivation, is potently accelerated by copper through multi-pronged mechanisms that converge on iron-dependent lipid peroxidation [61, 62]

As a key beneficial genus within the gut microbiota, Bifidobacterium contributes to gut homeostasis through the secretion of SCFAs and suppression of pathogenic bacterial proliferation [37, 38]

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However, the pharmacokinetic characteristics, tissue bioaccumulation, and toxicity profiles of arsenic metabolites in vivo following oral administration of ATO have not yet been characterized

Drug Delivery, 28 (1), 136144