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[DOI] [PubMed] [Google Scholar] 372.Rajeswari A, and Sabesan M

doi: 10.1016/j.pnpbp.2004.05.009

Cell viability assay Cell viability was assessed using the Cell Counting Kit-8 (beyotime, C0038)

T.RichardsonN

Based on the in vitro studies on IDH mutant cells that have proven the antitumor efficacy of glutaminase inhibitor [144, 145], it is very likely that the beneficial effect of 2KG depletion on mutant IDH enzymes outweighs its unwanted effect on 2KG dependent dioxygenases