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These adjuvants were chosen for their clinical relevance and proven ability to elicit broad immune responses, including diverse effector T cell subsets and functional antibodies across multiple species ( , an adjuvant used in licensed influenza vaccines ( 2 Results 2.1 Identification and selection of mycobacterial antigens Building on the work of Bettencourt et al

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[199] A research letter published in JAMA reported that the vaccines appeared to be safe for immunosuppressed organ transplant recipients, but that the resulting antibody response was considerably poorer than in the non-immunocompromised population after only one dose

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Besides to modulate the mitochondrial redox status, ALA has further been reported to be implicated in the lipid regulation through its critical roles in modulating several key enzymes such as hydroxymethylglutaryl-CoA reductase (HMG-CoA reductase) and lipoprotein lipase (LPL) (33)