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We also observed statistically significant reduction in the protein levels of Complex II (quantified by densitometry in Fig

On the other hand, systemic immune dysregulation is exemplified in systemic lupus erythematosus (SLE), where neutrophil ferroptosis synergizes with CaMKIV-CREM pathway-mediated GPX4 suppression to potentiate NETosis (Li et al., 2021)

(6) When to pursue functional testing despite a high value Functional markers are most useful when the clinical picture argues for deficiency even though the total looks fine