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To do this effectively, the liver relies on a process called conjugation, where toxic substances are chemically modified and rendered less harmful so they can be excreted from the body

SUMMARY Clonorchis sinensis , Opisthorchis viverrini , and Opisthorchis felineus are important liver flukes that cause a considerable public health burden in eastern Asia, southeastern Asia, and eastern Europe, respectively

However, simultaneous impairment of both pathways induces oxidative stress and inflammation, culminating in severe hepatic injury [203]