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Phase IIb, randomized, double-blind trial of GC4419 versus placebo to reduce severe oral mucositis due to concurrent radiotherapy and cisplatin for head and neck cancer

For example, the DeepSynergy method uses deep learning to integrate chemical and genomic information to predict the synergy of drug combinations

Kinetic data for GSTM1a-1a indicate that kcat(CDNB) for the reaction is more than 3 times greater than kcat(FDNB), even though the nonenzymatic second-order rate constant is more than 50-fold greater for 1-fluoro-2,4-dinitrobenzene (FDNB), and the product is the same for both substrates

In some people, kojic acid can increase the skin's vulnerability to sunburn

Additionally, the upstream regulators and specific isoforms involved in this pathway remain to be identified