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Decreased muscle GSH content and the GSH:GSSG ratio

Available online 13 November 2017 References D.GiustariniI.Dalle-DonneD.TsikasR.RossiOxidative stress and human diseases: origin, link, measurement, mechanisms, and biomarkersCrit Rev Clin Lab Sci462009241281 K.RahmanStudies on free radicals, antioxidants, and co-factorsClin Intervent Aging22007219 V.LoboA.PatilA.PhatakN.ChandraFree radicals, antioxidants and functional foods: impact on human healthPharmacogn Rev42010118 S.HercbergP.GalanP.PreziosiThe SU

ALT, alanine aminotransferase (050 U/L)

Accession numbers for RNA-seq data on are as follows: ERS14340821, ERS14340822, ERS14340823, ERS14340824 (in vivo samples) and ERS2515249, ERS2515250, ERS2515251, ERS2515252 (in vitro samples)