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10.5664/jcsm.26657 J Clin Sleep Med

In our targeted single cell RNA-sequencing experiment, we observed that after 6 months of zinc supplementation, naive CD8+ T cells increased the expression of genes associated with maturation (PIK3IP, TRAC), differentiation and migration to the lymph nodes (CCR7) where they develop immune responses to novel viral or tumoral antigens

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In cohort 1B, efficacy was greater according to PD-L1 expression: 63.2% (PD-L1 90% of cases) and other solid tumors, implicated in their pathogenesis and invasiveness [84-86]