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Dual modification of BMAL1 by SUMO2/3 and ubiquitin promotes circadian activation of the CLOCK/BMAL1 complex

Cell Rep 2018;24, 1939-1948 e1934, doi:10.1016/j.celrep.2018.07.072

After 2 days, cells were transferred on 24-well plates for growth curve determination and SA--Gal Staining

Androgens coordinately induce the enzymatic activities of key polyamine biosynthetic enzymes, ornithine decarboxylase (ODC), S-adenosylmethionine decarboxylase (SAMDC), and spermidine synthase (SDS), with predominant expression localized to prostatic glandular epithelial cells (5961)

A investigao neurolgica explorou a interao do BPC-157 com o sistema nervoso central, incluindo os seus efeitos nas vias serotoninrgica e GABArgica