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3 Mechanisms of drug resistance driven by tumor heterogeneity Tumor heterogeneity enables therapeutic resistance through interconnected genetic, epigenetic, phenotypic, and microenvironmental mechanisms that coexist within tumors and interact, as summarized in Table 1 and Figure 1 , to generate drug-tolerant subpopulations that enable early resistance, underscoring the need for molecularly resolved, evolution-aware treatment strategies

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Through a series of optimization, we developed RT that enables quantitative real-time imaging of GSH in living cells

Johnston RB., Jr

None of it is fabricated