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doi:10.1016/j.ejpb.2018.05.009 Return to citation in text: [1] Gnger, S

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Mechanistically, elevated BCAA slevels exacerbate oxidative stress through two distinct pathways: (i) increased circulating BCAAs enhance ROS production in peripheral blood mononuclear cells (PBMCs) via mTOR signaling hyperactivation, resulting in PBMC overactivation (Zhenyukh et al., 2017)