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A small trial in methotrexate (MTX)-resistant RA suggested that everolimus plus MTX could alleviate joint symptoms, though larger confirmatory studies are needed (244)

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Similar content being viewed by others Introduction In the tumor microenvironment (TME), malignant cells and stromal cells produce various angiogenic factors to induce neovascularization, vascular remodeling, tumor growth, and metastasis 1