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The skin attributes improved at 12 weeks (as assessed by blind expert graders) for elasticity, wrinkles, and evenness in different body areas (face, hands, neck, etc.) compared with placebo measurements

Apart from the conventional application in advanced PD, DBS has also been suggested to exert disease-modifying traits (McKinnon et al

10.3892/or.2019.7189 426 YueC.ShanZ.TanY.YaoC.LiuY.LiuQ.et al

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During the development of osteoarthritis, the synovium undergoes interstitial vascularization, fibrosis and hyperplasia (167), and macrophages and fibroblasts in the synovium can release proinflammatory cytokines, etc., which cause synovitis and cartilage degeneration