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However, the flat surface of Ras proteins that precludes the binding of small-molecule inhibitors has hindered the development of effective drugs for cancer treatment, since the affinity of the reported small compounds is in the micromolar range 45,46,47,48 and below the required value for clinical applications 49

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Furthermore, the present disclosure also relates to methods of using the disclosed compositions to treat an injured tendon in a subject

En cas de difficult avaler, la glule peut tre ouverte