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References 1 AgarwalP

Furthermore, genes that are exclusively expressed in biological males, such as the testes exclusive genes GPR64 and SPINT3 , accumulate deleterious mutations [111]

This pattern is not unique to tirzepatide but reflects the biology of obesity and metabolic adaptation

Non-alcoholic fatty liver disease (NAFLD) is the most common liver disease worldwide, characterized by an excessive hepatic fat accumulation in the absence of alcoholic abuse, steatogenic medications or others concomitant liver diseases (2)

This bidirectional, dynamic framework, starting from the whole, analyzing at the molecular level, and feeding back into the whole, represents a practical path for quality control and bioavailability optimization in modern TCM