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In Europe, the European Medicines Agency supports two main regulatory tracks: well-established use and traditional use registration under Directive 2004/24/EC, which requires data on safety, efficacy, and pharmacovigilance

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Table 1 further elucidates the experimental parameters of these findings, summarizing key in vitro studies that highlight curcumins ability to target survival pathways and enhance chemosensitivity across various gastric cancer models