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However, in pathological states, excessive production of reactive oxygen species (ROS) can overwhelm the bodys antioxidant defenses, leading to inflammation and cellular damage, which are key contributors to gallstone development (1517)

Although elevated oxidative stress might contribute to fatigue, it is unclear in the literature whether the increase in glutathione concentrations through glutamine supplementation could attenuate fatigue and improve physical performance

10.1186/s13613-016-0198-5 55 CostaN

Functional and pharmacological evaluation of novel GLA variants in Fabry disease identifies six (two de novo) causative mutations and two amenable variants to the chaperone DGJ