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Glucose restriction extends Caenorhabditis elegans life span by inducing mitochondrial respiration and increasing oxidative stress

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This is made possible by recent advances in techniques that enable single-cell resolution analysis of the heart, including single-cell RNA sequencing (scRNA-seq), single-nucleus RNA sequencing (snRNA-seq), single-cell assay for transposase-accessible chromatin with sequencing (scATAC-seq), and spatial transcriptomics, which provide insights at the cellular and sub-cellular levels

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