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Thus, GSH may serve as a cofactor that facilitates loading and stabilization of the substrate in the transporter cavity

doi: 10.3389/fphar.2025.1665715 Received 14 July 2025 Accepted 08 September 2025 Published 24 September 2025 Volume 16 - 2025 Edited by Alexei Bagrov, Padakonn Pharma, Estonia Reviewed by Rubn G

The analysis of the catalytic parameters demonstrated a reaction rate of 0.0257 h 1 , turnover number of 38.2, and turnover frequency of Ru(II)-OH of 0.3141 h 1 (Supplementary Table 1)