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Layered structure The typical layered structure of GO with the privilege of having oxy-functional groups (hydroxyl, epoxide, and carboxyl groups) on its surface is critical as it significantly impacts its properties and expands the range of applications in different fields 99,100,101

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Similarly, in vitro and in vivo experiments in rodent models have demonstrated that hyperglycaemia alters the function of key plasticity molecules, such as growth-associated protein 43 (GAP43