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G., Stigge-Kaufman, D

10.1002/tox.22510 163 SinghB

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Histological analysis further confirmed substantial improvement in tendon healing quality after 2 weeks of treatment ( Despite its therapeutic potential, rhIGF-1 encounters several clinical limitations, primarily due to its structural homology with insulin, which may lead to hypoglycemia and growth hormone (GH) suppression ( in vivo half-life and susceptibility to proteolytic degradation